Guidance on the safety assessment of Enterococcus faecium in animal nutrition

Enterococcus faecium, guidance, safety, ampicillin, IS16, esp, hylEfm
First published in the EFSA Journal
23 mai 2012
25 avril 2012


This Guidance document is intended to provide a method to identify Enterococcus faecium strains belonging to a sub-population of bacteria isolated from clinical specimens. Differentiation is based on susceptibility to ampicillin and the absence of three genetic markers associated with the clinical isolates. In the view of the FEEDAP Panel any strain of E. faecium demonstrating a resistance to ampicillin greater than 2 mg/L or possessing any of the three marker genes should not be used as a feed additive.

Panel members at the time of adoption

Gabriele Aquilina, Georges Bories, Andrew Chesson, Pier Sandro Cocconcelli, Joop de Knecht, Noël Albert Dierick, Mikolaj Antoni Gralak, Jürgen Gropp, Ingrid Halle, Christer Hogstrand, Reinhard Kroker, Lubomir Leng, Secundino López Puente, Anne-Katrine Lundebye Haldorsen, Alberto Mantovani, Giovanna Martelli, Miklós Mézes, Derek Renshaw, Maria Saarela, Kristen Sejrsen and Johannes Westendorf
Panel on Additives and Products or Substances used in Animal Feed
EFSA Journal 2012;10(5):2682
Question Number
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