Refined risk assessment regarding certain maximum residue levels (MRLs) of concern for the active substance chlorpyrifos

chlorpyrifos, MRL review, Regulation (EC) No 396/2005, consumer risk assessment, organophosphate, insecticide, 3,5,6-trichloropyridinol
First published in the EFSA Journal
12 June 2015
9 June 2015
Reasoned Opinion


In compliance with Article 43 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) received from the European Commission (EC) a mandate to provide its reasoned opinion on the existing maximum residue levels (MRLs) for chlorpyrifos which might lead to consumers intake concerns on the basis of the new toxicological reference values and of the data currently available to EFSA. In order to identify the potential MRLs of concern that require a more detailed assessment, EFSA performed a first unrealistically conservative intake calculation on the basis of the existing EU MRLs for chlorpyrifos. Those potential MRLs of concern were assessed in more detail by EFSA and where the safety of the existing EU MRLs could not be confirmed by the available data, possible measures for risk mitigation were assessed by EFSA.

European Food Safety Authority
pesticides.mrl [at]
EFSA Journal 2015;13(6):4142
Question Number
On request from
European Commission

Background documents