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Extensive literature review on plasticisers

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Disclaimer: The present document has been produced and adopted by the bodies identified above as author(s). This task has been carried out exclusively by the author(s) in the context of a contract between the European Food Safety Authority and the author(s), awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as an output adopted by the Authority. The European Food Safety Authority reserves its rights, view and position as regards the issues addressed and the conclusions reached in the present document, without prejudice to the rights of the authors.

Abstract

An extensive review of the literature was performed to identify scientific articles relevant to the exposure assessment of potential plasticiser substances. The initial search resulted in a database consisting of 21,453 papers provided by EFSA. The relevance analysis of the documents performed by screening of titles and abstracts and applying inclusion and exclusion criteria identified 582 documents. In a subsequent step, a full text screening was carried out for further study selection and categorisation and resulted in 383 relevant documents, distributed over the following 8 areas of interests: Area 1 (plasticisers in food) ‐ 72 references; Area 2 (dietary exposure) ‐ 30 references; Area 3 (market share and food chain) ‐ 21 references; Area 4 (migration of plasticisers) ‐ 65 references; Area 5 (packaged food) ‐ 9 references; Area 6 (non‐food use of plasticisers) ‐ 73 references; Area 7 (non‐dietary exposure to plasticisers) ‐ 88 references; Area 8 (overall exposure) ‐ 115 references. A data form was prepared, and high‐level information were extracted from each relevant reference, reporting information considered useful for the exposure assessment of potential plasticisers, in line with the areas of interest. In addition, a summary paragraph for each potential plasticiser was provided.