RNA interference

Description:

The blocking of normal gene activities by RNA molecules. This is a natural process but can also be harnessed by biologists as a way of researching how genes work in the body

Context:

RNA interference (RNAi) is a process in cells where small RNA molecules can “switch off” or silence specific genes. In food safety, RNAi can be used in crops to reduce the production of harmful substances, increase resistance to pests, or improve nutritional qualities without introducing foreign proteins.

EFSA evaluates the safety of RNAi-based products, such as genetically modified crops, by assessing potential effects on human and animal health, possible impacts on non-target organisms, and environmental risks. This helps ensure that RNAi applications in food and feed are safe before they are approved for use in the EU.