mode of action
Description:
A sequence of events, identified by research, which explains an observed effect
Context:
In food safety, a mode of action is the way a substance—like a chemical, contaminant, or additive—produces its effect in the body. It explains the steps or processes that lead to a specific response, whether harmful or beneficial.
EFSA uses knowledge of a substance’s mode of action to understand how it can affect human health. This helps predict potential risks, determine safe exposure levels, and identify sensitive groups. Understanding the mode of action is important for accurate risk assessments, informing regulations, and protecting consumers from harmful effects in the food chain.