co-resistance
Genetically-conferred resistance in an organism (e.g. the resistance of a plant to a disease) that results from two or more linked genes being passed down the generations
Co-resistance occurs when a microorganism, such as a bacterium, carries genes that make it resistant to more than one antibiotic or antimicrobial substance at the same time. These resistance genes are often located close together on the same piece of DNA, so selecting for resistance to one antibiotic can also select for resistance to others.
In the field of GMOs, co-resistance is relevant when genetically modified plants carry antibiotic resistance marker genes. EFSA evaluates these GM plants to check whether these genes could spread to bacteria in the environment or the gut, potentially contributing to antimicrobial resistance. EFSA’s assessment ensures that GMOs do not increase the risk of co-resistance, helping protect human and animal health.