Delta-8 THC: EFSA sets safe intake level

Delta-8 THC is a psychoactive cannabinoid occasionally detected in products from the hemp plant Cannabis sativa such as hemp leaves, seeds and oil. It is also detected in food products such as candies and supplements marketed as hemp products.

Consuming delta-8 THC impacts cognitive and psychomotor abilities and increases heart rate in a similar way to delta-9 THC, the main chemical responsible for the psychoactive effects of cannabis.

Considering the similarity in the effects and modes of action between delta-8 THC and delta-9 THC, EFSA scientists established that both chemicals have similar potency A measure of the capacity of a chemical substance to exert an effect, described in terms of the relationship between the dose used and the magnitude of the resulting effect. They concluded that the acute reference dose The total amount of a substance (e.g. a chemical or nutrient) given to, consumed or absorbed by an individual organism, population or ecosystem (ARfD) set in 2015 for delta-9 THC should apply to the total amount of delta-8 THC and delta-9 THC consumed together. The ARfD is 1 microgram (1 millionth of a gram) per kilogram of body weight per day.

Based on EFSA’s work, the European Commission and Member States will consider if regulatory measures are needed for delta-8 THC in food to protect consumers from potential health risks.

EFSA scientists also recommended that recent studies on delta-9 THC should be considered to re-evaluate its safety.