Hydroxyanthracene derivatives and improvement of bowel function


Transitech®, hydroxyanthracene derivatives, bowel function, health claims
First published in the EFSA Journal
30 October 2013
9 October 2013
Scientific Opinion

Following an application from Vivatech, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to hydroxyanthracene derivatives and improvement of bowel function. An improvement of bowel function such as reduced transit time, more frequent bowel movements, increased faecal bulk, or softer stools is a beneficial physiological effect, provided that it does not result in diarrhoea. The Panel notes that the effect of hydroxyanthracene derivatives from the root and rhizome of Rheum palmatum L. and/or Rheum officinale Baillon and/or their hybrids, from the leaves or fruits of Cassia senna L. and/or Cassia angustifolia Vahl, from the bark of Rhamnus frangula L., from the bark of Rhamnus purshianus D.C. and from Aloe barbadensis Miller and/or various aloe species, mainly Aloe ferox Miller and its hybrids on the short-term alleviation of occasional constipation is well established. The Panel concludes that a cause and effect relationship has been established between consumption of hydroxyanthracene derivatives and improvement of bowel function.

Panel members at the time of adoption
Carlo Agostoni, Roberto Berni Canani, Susan Fairweather-Tait, Marina Heinonen, Hannu Korhonen, Sébastien La Vieille, Rosangela Marchelli, Ambroise Martin, Androniki Naska, Monika Neuhäuser-Berthold, Grażyna Nowicka, Yolanda Sanz, Alfonso Siani, Anders Sjödin, Martin Stern, Sean (J.J.) Strain, Inge Tetens, Daniel Tomé, Dominique Turck and Hans Verhagen
Panel on Dietetic Products, Nutrition and Allergies
nda [at] efsa.europa.eu
EFSA Journal 2013;11(10):3412 [12 pp.].
Question Number
On request from
Competent Authority of France following an application by Vivatech
Print on demand
Number of Pages