Scientific Opinion on Flavouring Group Evaluation 215 (FGE.215): Seven α,β-Unsaturated Cinnamyl Ketones from subgroup 3.2 of FGE.19
Meta data
Keywords
α,β-unsaturated aldehydes, straight chain, FGE.215, α,β-unsaturated cinnamyl ketones, subgroup 3.2, FGE.19
On request from
European Commission
Question Number
EFSA-Q-2013-00668
EFSA-Q-2013-00669
EFSA-Q-2013-00670
EFSA-Q-2013-00671
EFSA-Q-2013-00672
EFSA-Q-2013-00673
EFSA-Q-2014-00125
Panel members at the time of adoption
Ulla Beckman Sundh, Mona-Lise Binderup, Claudia Bolognesi, Leon Brimer, Laurence Castle, Alessandro Di Domenico, Karl-Heinz Engel, Roland Franz, Nathalie Gontard, Rainer Gürtler, Trine Husøy, Klaus-Dieter Jany, Martine Kolf-Clauw, Wim Mennes, Maria Rosaria Milana, Iona Pratt †, Kettil Svensson, Maria de Fátima Tavares Poças, Fidel Toldrá and Detlef Wölfle
Contact
Abstract
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of flavouring substances from subgroup 3.2 of FGE.19 in the Flavouring Group Evaluation 215 (FGE.215). The Flavour Industry has provided in vitro genotoxicity studies for the representative substances in FGE.215, namely 4-phenylbut-3-en-2-one [FL-no: 07.024] and 1-(4-methoxyphenyl)pent-1-en-3-one [FL-no: 07.030]. Based on these genotoxicity data, the Panel concluded that the genotoxicity concern could not be ruled out and in vivo genotoxicity data are requested.
© European Food Safety Authority, 2014