Scientific conference on the use of epidemiological findings in regulatory pesticide risk assessment

Parma, Italy
21 November 2017

EFSA is organising a scientific conference with stakeholders to discuss a series of activities it has carried out in the past two years in the area of pesticides. In particular, discussions will focus on EFSA’s Scientific Opinion investigating the experimental toxicological properties of plant protection products having a potential link to Parkinson’s disease and childhood leukaemia and its draft opinion dealing with the methodological limitations of epidemiological studies – currently under public consultation – which will make recommendations for improving the studies to facilitate their integration into regulatory pesticide risk assessment.


21 November 2017, NH Hotel in Parma, Italy

Time Topic


Opening remarks
Jose Tarazona, EFSA

1st session - Chair: Jose Tarazona, EFSA


Introduction to the “EFSA Epidemiology project”
Federica Crivellente, EFSA


Scientific Opinion on the investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson’s disease and childhood leukaemia
Susanne Hougaard Bennekou, Danish EPA, EFSA PPR Panel


Applicability of the AOP for assessing causality of observations in epidemiological studies
Bette Meek, University of Ottawa, Canada


Scientific Opinion of the PPR Panel on the follow-up of the findings of the External Scientific Report “Literature review of epidemiological studies linking exposure to pesticides and health effects”
Antonio Hernandez Jerez, University of Granada, EFSA PPR Panel


The US EPA’s approach to Pesticide Epidemiology: similarities and differences with the EFSA proposal
David Miller, US-EPA


Integrating epidemiological data in hazard identification
Dana Loomis, IARC


The AOP conceptual framework as a tool to support biological plausibility of epidemiological studies. Practical example: inhibition of the mitochondrial complex I of nigrostriatal neurons leading to Parkinson motor deficits.
Karin Angeli, ANSES


Coffee break

2nd session - Chair: Christine Müller-Graf, BfR


The Agricultural Health Study (AHS)
Laura Beane Freeman, US National Cancer Institute


Exposure data in environmental epidemiology: limitations and quality assessments
Judy Lakind, LaKind Associates


Pesticide exposure assessment in epidemiological studies. Current issues and future perspective
Laura Beane Freeman, US National Cancer Institute


Contribution of vigilance data to the risk assessment of pesticides
Marie-Odile Rambourg, ANSES


Critical review of EFSA proposal and ways to implement the use of epidemiology in pesticide risk assessment
Manolis Kogevinas, ISGlobal, Barcelona, President International Society for Environmental Epidemiology (ISEE)



Afternoon session - Chair:Jose Tarazona, EFSA


Perspectives on environmental epidemiology
Carol Burns, ECPA


Considerations on the approach proposed by EFSA
Francois Veillerette, President PAN Europe


Open discussion


Concluding remarks
Laura Fabrizi, DG Santé


End of the Scientific Conference

Who should attend

The aim of the conference is to collect views from stakeholders and further discuss the approach proposed by EFSA in its two scientific opinions. Participation is limited to experts in the field of pesticide epidemiology and regulatory risk assessment of pesticides. Participants will be selected to ensure a sufficient representation of the various fields of expertise, as well as a broad geographical balance.

Registration will close once the maximum number of participants is reached or, at the latest, by 06 November 2017.

After closure of registration, potential participants will be informed whether or not they have been selected.

Date and venue

The conference will be held on 21 November, 2017, at the NH Hotel in Parma, northern Italy.


English will be the official language of the conference. No translation will be provided.


Feel free to contact us about any content-related matters or organisational and logistical issues at the following address: conferences [at]