Following a request from the European Commission, EFSA developed updated scientific guidance to assist applicants in the preparation of applications on smoke flavouring primary products. This guidance describes the scientific data to be included in the ap ...
This report presents the implementation of a web tool for the extension of exposure‐and toxicokinetic‐toxicodynamic analysis that has been developed under aspecific EFSA request to Open Analytics under the framework agreement (OC/EFSA/AMU/2015/02).An open ...
In this project we set up a human cell‐based DNT in vitro testing strategy that is based on test methods with high readiness and data generated therefrom. The methods underwent afit‐for‐purpose evaluation that considered four key elements: 1. The test sys ...
This final report summarises the objectives, activities and delivery, evaluation, and any future recommendations for each of the four trainings delivered under this contract. Sections are organised in chronological order consistent with the order in which ...
In specific contract No 18 issued under the framework agreement OC/EFSA/AMU/2015/02, EFSA requested Open Analytics to develop software implementing the workflow of a ranking process in a web application.This tool assists ranking objects in a transparent, ...
EFSA requested its Scientific Committee to prepare a guidance document on appraising and integrating evidence from epidemiological studies for use in EFSA's scientific assessments. The guidance document provides an introduction to epidemiological stu ...
Dose‐response meta‐analyses are of key relevance to identify causal relations between exposure and health‐related endpoints based on epidemiologic evidence, thus providing a powerful tool for both investigators and risk assessors. So far, their use has be ...
In specific contract No 13 issued under the framework agreement OC/EFSA/AMU/2015/02, EFSA requested Open Analytics to implement a web application for operator exposure calculation. The software is developed in R and consists of a WEB‐based tool composed b ...
The Mixed‐lineage leukemia (MLL) gene constitutes a genomic hotspot commonly rearranged/translocated in human acute leukemia (AL). MLL rearrangements (MLL r) represent a common hallmark of both de novo AL and therapy‐related acute myeloid leukemia (t‐AML) ...
To harmonise vertebrate OECD Test Guidelines for endocrine disruption testing between mammalian and non‐mammalian test species, additional Estrogen, Androgen, Thyroid and Steroidogenesis (EATS) modality endpoints in non‐mammalian models need to be assesse ...