In this project we set up a human cell‐based DNT in vitro testing strategy that is based on test methods with high readiness and data generated therefrom. The methods underwent afit‐for‐purpose evaluation that considered four key elements: 1. The test sys ...
An extensive literature search to identify and collect studies related to the toxicity of grayanotoxins and 5‐hydroxymethylfurfural (5‐HMF) was performed in the three databases PubMed, Web of Science and SciFinder ® for six and four Areas, respectively. A ...
The Mixed‐lineage leukemia (MLL) gene constitutes a genomic hotspot commonly rearranged/translocated in human acute leukemia (AL). MLL rearrangements (MLL r) represent a common hallmark of both de novo AL and therapy‐related acute myeloid leukemia (t‐AML) ...
To harmonise vertebrate OECD Test Guidelines for endocrine disruption testing between mammalian and non‐mammalian test species, additional Estrogen, Androgen, Thyroid and Steroidogenesis (EATS) modality endpoints in non‐mammalian models need to be assesse ...
The present document is a summary of the activities undertaken during the first year of the framework contract (OC/EFSA/SCER/2018/01) undertaken for the maintenance, update and further development of EFSA's chemical Hazards database “OpenFodTox 2.0”. ...
PERSAM is a software tool for predicting environmental concentrations of plant protection products (PPPs) in soil commissioned by EFSA. The PERSAM tool was first launched in 2013. In support of the EFSA Guidance Document for predicting environmental conce ...
PERSAM is a software tool for predicting environmental concentrations of plant protection products (PPPs) in soil commissioned by EFSA. The PERSAM tool was first launched in 2013. In support of the EFSA Guidance Document for predicting environmental conce ...
PERSAM is a software tool for predicting environmental concentrations of plant protection products (PPPs) in soil commissioned by EFSA. The PERSAM tool was first launched in 2013. In support of the EFSA Guidance Document for predicting environmental conce ...
PERSAM is a software tool for predicting environmental concentrations of plant protection products (PPPs) in soil commissioned by EFSA. The PERSAM tool was first launched in 2013. In support of the EFSA Guidance Document for predicting environmental conce ...
This report presents the outcome of extensive literature search on studies related to the chemistry and toxicity of glycoalkaloids and quinolizidine alkaloids in food and feed. The systematic literature search captures available scientific information pub ...