We are holding a workshop to disseminate the revised methodology for benchmark dose (BMD) analysis in EFSA’s updated Guidance document and to support its implementation in the R4EU BMD analysis platform.
In 2009, EFSA’s Scientific Committee developed guidance on the use of the BMD approach in EFSA’s risk assessments as an alternative to the traditional No-Observed-Adverse-Effect-Level (NOAEL) approach. A 2017 update mainly concerned how to apply the BMD approach in practice and model averaging was introduced to account for model uncertainty.
Following an EFSA workshop in March 2017 to discuss commonalities and divergences in the various approaches for BMD analysis worldwide, and the update of Chapter 5 on dose– response assessment of WHO/IPCS Environmental Health Criteria 240 (WHO, 2020), the Scientific Committee decided to update its guidance again to align it with internationally agreed concepts related to benchmark dose analysis, introducing Bayesian model averaging and a harmonised set of dose-response models for continuous and quantal responses, further harmonising EFSA’s approach with its partners.
The latest updated Guidance was published on 25 October 2022.
Structure of the meeting
The event takes place in the afternoon of 15 February and in the morning of 16 February, and is divided in two parts:
- Presentation of the new guidance, changes to the previous version, and EFSA’s recommended approach for BMD analysis.
- Illustration of the new approach, using the EFSA BMD analysis platform with pesticides-related case studies.
During the event, the audience can submit questions to the speakers and interact with the presenters.
Who should attend?
This event is open to risk assessors and all stakeholders involved or interested in the use of the benchmark dose (BMD) approach in risk assessment.
How to register
Registrations to this event are closed.
Do not hesitate to contact us at events [at] efsa.europa.eu for more information.
The event will be webstreamed. Therefore, you are invited to connect to the webpage on 15 February, starting from 14.00, where direct access to the webstream will be made available: