Outcome of the public consultation on the draft guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment

Threshold of toxicological concern, risk assessment, Cramer classification scheme.
First published in EFSA Supporting Publications
6 June 2019
17 May 2019
Technical Report


The European Food Safety Authority (EFSA) carried out a public consultation to receive input from the scientific community and all interested parties on the Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment. The draft guidance was prepared by a dedicated working group of the Scientific Committee and endorsed by the Scientific Committee for public consultation at its plenary meeting of 17th September 2018. The public consultation for this document was open from 12th November 2018 to 10th January 2019. EFSA received 101 comments from 23 interested parties in addition to three letters. EFSA’s Scientific Committee wishes to thank all stakeholders for their contributions. This report presents statistics on the comments received and provides a summarised description of how the comments were addressed in the finalisation of the document. The valuable and detailed comments from the stakeholders were taken into account by the Scientific Committee to prepare an updated version of the guidance. The opinion was discussed and adopted at the Scientific Committee plenary meeting on 24 April 2019 and is published in the EFSA Journal

sc.secretariat [at] efsa.europa.eu
EFSA Supporting publication 2019:EN-1661
Question Number
On request from
European Food Safety Authority