The present document is a summary of the activities undertaken during the first year of the framework contract (OC/EFSA/SCER/2018/01) undertaken for the maintenance, update and further development of EFSA's chemical Hazards database “OpenFodTox 2.0”. ...
There is a fundamental change in thinking within the regulatory community due to a better understanding of the underlying biology of adverse effects to human health and the environment. The development of alternatives to use laboratory animals has become ...
This scientific report provides a review of modern methodologies and tools to depict toxicokinetic and toxicodynamic processes and their application for the human hazard assessment of chemicals. The application of these methods is illustrated with example ...
No abstract available doi: 10.2903/j.efsa.2012.2539 Question Number: EFSA-Q-2010-01162 Journal Number: EFSA Journal 2012;10(1):2539 Panels: Panel on Additives and Products or Substances used in Animal Feed Panel members at the time of adoption: Gabri ...
Following a request from the European Commission, the Scientific Committee developed principles and guidance for the establishment of protocols for 90-day whole food/feed studies in rodents. The guidance complements the OECD Test guideline 408 and provide ...
No abstract available Keywords: methods, in vivo methods, animal welfare, alternative risk assessment testing strategies, replacement, reduction, refinement doi: 10.2903/j.efsa.2009.1052 Question Number: EFSA-Q-2005-231 Panel members at the time of ado ...