Calystegines are polyhydroxylated nortropane alkaloids that have been found in various solanaceous foods, in particular in potatoes and aubergines. The biological activity and potential toxicity of calystegines are associated with their capacity to inhibi ...
EFSA was requested to provide scientific assistance to the European Commission on a detoxification process for dioxins and PCBs from sunflower cake by hexane extraction in an emergency situation, as specified in Article 7 of Commission Regulation (EU) 201 ...
Heat processing of food gives rise to a plethora of chemical compounds whose toxicological effects are largely unknown. Due to a general lack of experimental toxicological data, assessing the risks associated with the consumption of these substances remai ...
The European Commission requested EFSA to evaluate whether a series of dyes are covered by the ‘Guidance on methodological principles and scientific methods to be taken into account when establishing Reference Points for Action (RPAs) for non‐allowed phar ...
The European Commission asked the European Food Safety Authority (EFSA) to review the evaluation of zilpaterol hydrochloride (zilpaterol) by the 81st meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and to assess the available scien ...
There is a fundamental change in thinking within the regulatory community due to a better understanding of the underlying biology of adverse effects to human health and the environment. The development of alternatives to use laboratory animals has become ...
Different organisations have undertaken risk assessments of dioxins resulting in the issuance of a range of health-based guidance values. This report examines the approaches taken by the Scientific Committee on Food (SCF), the Joint FAO/WHO Expert Committ ...
The Commission requested EFSA to assess three studies concerning the use of rubber slats in pig holdings regarding the statistical differences between the welfare outcomes for sows and gilts when comparing concrete slatted floors and floors with a rubber ...
This scientific report provides a review of modern methodologies and tools to depict toxicokinetic and toxicodynamic processes and their application for the human hazard assessment of chemicals. The application of these methods is illustrated with example ...
Arsenic is a ubiquitous metalloid present at low concentrations in rocks, soil and natural ground water. A total of 103 773 food samples (including drinking water) were used to calculate dietary exposure to inorganic arsenic (iAs). Of these, 101 020 were ...