A survey to overview the presence of pollen supplements and substitutes for bees and other animal species in the EU was conducted to serve as input for the regulatory risk assessment of genetically modified feed by the EFSA GMO Panel. A comprehensive mapp ...
Clear guidance on conducting Environmental Risk Assessment (ERA) of nanomaterials is becoming more and more relevant as new applications of nanomaterials in the food and feed chain are developed. Upon request from EFSA, this report compiles and structures ...
In this project we set up a human cell‐based DNT in vitro testing strategy that is based on test methods with high readiness and data generated therefrom. The methods underwent afit‐for‐purpose evaluation that considered four key elements: 1. The test sys ...
This report is the outcome of an EFSA procurement (NP/EFSA/GMO/2018/01) reviewing relevant scientific information on in silico prediction methods for protein toxicity, that could support the food and feed risk assessment. Several proteins are associated w ...
This report describes the tasks performed in the period 6/12/2019 to 16/07/2020under the EFSA contract OC/EFSA/GMO/2018/02, Lot 2 on toxicological studies and animal feeding studies included in applicationsfor market authorisation of genetically modified ...
The Mixed‐lineage leukemia (MLL) gene constitutes a genomic hotspot commonly rearranged/translocated in human acute leukemia (AL). MLL rearrangements (MLL r) represent a common hallmark of both de novo AL and therapy‐related acute myeloid leukemia (t‐AML) ...
This report describes the tasks performed in the period 28/11/2018 to 5/12/2019under the EFSA contract OC/EFSA/GMO/2018/02, Lot 2 on toxicological studies and animal feeding studies included in applicationsfor market authorisation of genetically modified ...
To harmonise vertebrate OECD Test Guidelines for endocrine disruption testing between mammalian and non‐mammalian test species, additional Estrogen, Androgen, Thyroid and Steroidogenesis (EATS) modality endpoints in non‐mammalian models need to be assesse ...
The primary objective of the assessment of novel proteins is to evaluate whether they are safe to consume, including potential allergenicity. As part of a suite of assessments, the in vitro digestion of protein has been seen as a useful exercise. Thus, in ...
PERSAM is a software tool for predicting environmental concentrations of plant protection products (PPPs) in soil commissioned by EFSA. The PERSAM tool was first launched in 2013. In support of the EFSA Guidance Document for predicting environmental conce ...