The Scientific Committee confirms that the Threshold of Toxicological Concern (TTC) is a pragmatic screening and prioritisation tool for use in food safety assessment. This Guidance provides clear step‐by‐step instructions for use of the TTC approach. The ...
This document provides guidance for communicators on how to communicate the various expressions of uncertainty described in EFSA's document: ‘Guidance on uncertainty analysis in scientific assessments’. It also contains specific guidance for assessor ...
Heat processing of food gives rise to a plethora of chemical compounds whose toxicological effects are largely unknown. Due to a general lack of experimental toxicological data, assessing the risks associated with the consumption of these substances remai ...
The currently applied approaches, procedures and tools used for the identification of emerging risks vary greatly among Member States of the EU. EFSA established a structured approach for emerging risk identification that mainly consists of systematically ...
This Guidance describes how to perform hazard identification for endocrine-disrupting properties by following the scientific criteria which are outlined in Commission Delegated Regulation (EU) 2017/2100 and Commission Regulation (EU) 2018/605 for biocidal ...
There is a fundamental change in thinking within the regulatory community due to a better understanding of the underlying biology of adverse effects to human health and the environment. The development of alternatives to use laboratory animals has become ...
The history of agriculture includes many animal and plant disease events that have had major consequences for the sector, as well as for humans. At the same time, human activities beyond agriculture have often driven the emergence of diseases. The more th ...
Statistical analyses are an essential part of risk assessments. Statistical reporting varies considerably amongst the documents that EFSA receives and produces, which can lead to lack of transparency and reproducibility of results. This guidance aims to i ...
Quantitative risk assessments facilitate the decisions of risk managers. In the EU, risk assessment in food and feed safety is the responsibility of the European Food Safety Authority (EFSA). Quantitative risk models should be informed by systematically r ...
EFSA was asked by the Commission to prepare an EFSA Guidance document on clustering and ranking of emissions of active substances of plant protection products (PPPs) and transformation products of these active substances from protected crops (greenhouses ...