Establishment of cumulative assessment groups of pesticides for their effects on the thyroid

cumulative risk assessment, cumulative assessment groups, pesticides mixtures, hypothy-roidism
First published in the EFSA Journal
17. September 2019
26. Juni 2019
Scientific Report


Cumulative assessment groups of pesticides have been established for two specific effects on the thyroid: firstly hypothyroidism, and secondly parafollicular cell (C‐cell) hypertrophy, hyperplasia and neoplasia. Sources of uncertainties resulting from the methodological approach and from the limitations in available data and scientific knowledge have been identified and considered. This report supports the publication of a scientific report on cumulative risk assessment to pesticides affecting the thyroid, in which all uncertainties identified for either the exposure assessment or the establishment of the cumulative assessment groups are incorporated into a consolidated risk characterisation.

European Food Safety Authority
pesticides.mrl [at]
EFSA Journal 2019;17(9):5801
Question Number
On request from