Safety of ethyl ester of β‐apo‐8’‐carotenoic acid as a feed additive for poultry for fattening and poultry for laying

ethyl ester of β‐apo‐8’‐carotenoic acid, safety, poultry, colourant
First published in the EFSA Journal
18 dicembre 2019
Adopted
12 novembre 2019
Type
Scientific Opinion

Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the additional data submitted for ethyl ester of β‐apo‐8‐carotenic acid (β‐apo‐8‐ester) when used as a feed additive for poultry for fattening and poultry for laying. The proposed maximum content for β‐apo‐8‐ester of 40 mg/kg complete feed is safe for laying hens with a margin of safety of at least two. The following dietary concentrations are considered safe for the adult consumers, including the age classes adults, elderly and very elderly: 15 mg β‐apo‐8‐ester/kg complete feed for chickens for fattening, 5 mg β‐apo‐8‐ester/kg complete feed for laying hens and 40 mg β‐apo‐8‐ester/kg complete feed for laying hens only intended to the production of liquid eggs which will be only used by the pasta industry for the production of egg pasta. Concerns would arise for the age classes infants, toddlers, other children and adolescents in those countries where dietary surveys showed higher consumption of egg and egg‐derived products (Bulgaria, Spain, the UK, the Netherlands, Greece, the Czech Republic and Italy) and higher consumption of egg pasta (Bulgaria, Spain, the UK, the Netherlands, Germany, Denmark, Greece, Austria, the Czech Republic, France, Latvia, Sweden and Italy) assuming that the egg pasta is manufactured with liquid eggs from laying hens treated with 40 mg β‐apo‐8‐ester/kg complete feed.

Substances
Ethyl ester of beta-apo-8'-carotenoic acid
Cas: 1109-11-1
Inchi: InChI=1S/C32H44O2/c1-9-34-31(33)29(6)20-13-19-26(3)16-11-10-15-25(2)17-12-18-27(4)22-23-30-28(5)21-14-24-32(30,7)8/h10-13,15-20,22-23H,9,14,21,24H2,1-8H3/b11-10+,17-12+,19-13+,23-22+,25-15+,26-16+,27-18+,29-20+
Iupac: ethyl (2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohexen-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenoate

Panel members at the time of adoption

Giovanna Azimonti, Vasileios Bampidis Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Kos Durjava, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa and Ruud Woutersen.
Panel on Additives and Products or Substances used in Animal Feed
Contact
feedap [at] efsa.europa.eu
doi
10.2903/j.efsa.2019.5911
EFSA Journal 2019;17(12):5911
Question Number
On request from
European Commission