Statement on the safe use of the nptII antibiotic resistance marker gene in genetically modified plants by the Scientific Panel on genetically modified organisms (GMO)

doi:10.2903/j.efsa.2007.742
  EFSA Panel on Genetically Modified Organisms Panel Members Hans Christer Andersson, Salvatore Arpaia, Detlef Bartsch, Josep Casacuberta, Howard Davies, Lieve Herman, Marc De Loose, Niels Hendriksen, Sirpa Kärenlampi, Jozsef Kiss, Ilona Kryspin-Sørensen, Harry Kuiper, Ingolf Nes, Nickolas Panopoulos, Joe Perry, Annette Pöting, Joachim Schiemann, Willem Seinen, Jeremy Sweet, and Jean-Michel Wal. Acknowledgment The GMO Panel wishes to thank Hans Jörg Buhk, Patrick Du Jardin, Boet Glandorf, John Heritage, Fergal O’Gara, Armine Sefton, Philippe Vain, and Jan Dick van Elsas for their contributions to the statement.
Type: Statement of the Scientific Committee/Scientific Panel Adopted: 22 March 2007 Published: 13 April 2007 Last updated: 13 April 2007. This version replaces the previous one/s.
Abstract

No abstract available

Summary

The Commission is currently considering the authorisation for placing on the market of the genetically modified (GM) potato line EH92-527-1 under Regulation (EC) No 1829/2003 on GM food and feed and under Directive 2001/18/EC, part C. The GM potato, developed for amylopectin production, also contains a nptII gene used as a selectable marker. The nptII gene codes for an aminoglycoside phosphotransferase conferring resistance to antibiotics such as kanamycin, neomycin, paromomycin, butirosin, gentamycin B and geneticin.