This reporting manual provides guidance for reporting on zoonoses and zoonotic agents in animals, food and feed under the framework of Directive 2003/99/EC. Instruction is also provided on the reporting of other pathogenic microbiological agents in food. The objective is to harmonise and streamline reporting by Member States to ensure that the data collected are relevant and easy to analyse at the European Union level. This manual covers all the zoonoses and zoonotic agents included under the current data collection system run by the European Food Safety Authority. Detailed guidelines are provided on reporting data in both table and text form. This guidance applies to the agents, animal species and food categories to be reported on. Instructions are given on describing the sampling and monitoring schemes, as well as analysing the results in the national reports. Special reference is made to fields in which following trends would be desirable. This manual is specifically aimed at guiding the reporting of information deriving from the year 2014.