This report presents the outcome of extensive literature search on studies related to the chemistry and toxicity of glycoalkaloids and quinolizidine alkaloids in food and feed. The systematic literature search captures available scientific information pub ...
This study applied a procedure for the identification of potential emerging chemical risks in the food chain to substances registered under the REACH Regulation that was previously developed and tested in an EFSA‐sponsored pilot study. The selection was l ...
EFSA defines ‘chemical mixtures’ as ‘several substances which may have combined effects on the body from their combined exposures’. There are already some methodologies for assessing risks from combined exposure to groups of chemicals, and EFSA together w ...
Calystegines are polyhydroxylated nortropane alkaloids that have been found in various solanaceous foods, in particular in potatoes and aubergines. The biological activity and potential toxicity of calystegines are associated with their capacity to inhibi ...
The EFSA Scientific Committee addressed in this document the peculiarities related to the genotoxicity assessment of chemical mixtures. The EFSA Scientific Committee suggests that first a mixture should be chemically characterised as far as possible. Alth ...
EFSA was requested to provide scientific assistance to the European Commission on a detoxification process for dioxins and PCBs from sunflower cake by hexane extraction in an emergency situation, as specified in Article 7 of Commission Regulation (EU) 201 ...
Polychlorinated dibenzodioxins (PCDD), polychlorinated dibenzofurans (PCDFs) and dioxin‐like polychlorinated biphenyls (DL‐PCBs) are detected ubiquitously in the environment, diet and human tissues. The European Food Safety Authority (EFSA) CONTAM Panel r ...
To enable the hazard identification and characterisation in the risk assessment for humans related to the seventeen 2,3,7,8‐substituted dioxins (PCCDs) and furans (PCDFs) and the twelve dioxin‐like polychlorinated biphenyls (DL‐PCBs), EFSA outsourced an e ...
The goal of the current work was to implement and verify previously published rat and human PBPK modelling codes for TCDD into Berkeley Madonna. The US‐EPA has used these PBPK models in the reassessment of TCDD. A procurement contract has been set up to e ...
This Report presents the results from EFSA project RC/EFSA/AMU/2016/01 related to the implementation of machine learning techniques for literature reviews and systematic reviews in EFSA. An overview of the different steps of a systematic review is provide ...