Low-fat fermented milk with a combination of fructo-oligosaccharides and live Lactobacillus rhamnosus GG (ATCC 53103), Streptococcus thermophilus

low-fat fermented milk; LGG ;fructo-oligosaccharides;Herpes simplex virus;health claims
First published in the EFSA Journal
19 July 2016
Adopted
28 June 2016
Type
Scientific Opinion

Abstract

Following an application from Granarolo S.p.A., submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to a low-fat fermented milk and defence against reactivation ofHerpes simplex virus (HSV) in the orolabial epithelia. The scope of the application was proposed to fall under a health claim based on newly developed scientific evidence. The food which is the subject of the health claim, a low-fat fermented milk with a combination of fructo-oligosaccharides and live Lactobacillus rhamnosus GG (ATCC 53103), Streptococcus thermophilus (Z57) and Lactobacillus delbrueckiisubsp. Bulgaricus (LB2), is sufficiently characterised. Defence against reactivation of HSV in the orolabial epithelia is a beneficial physiological effect. The Panel considers that no conclusions can be drawn from three out of the four human intervention studies, which were provided by the applicant, for the scientific substantiation of the claim. In weighing the evidence, the Panel took into account that one human intervention study from which scientific conclusions can be drawn does not show a consistent effect of daily consumption of the low-fat fermented milk on the reduction in incidence of herpes labialis (HL) lesions after ultraviolet B (UVB) exposure and that no convincing evidence was provided for a mechanism by which the low-fat fermented milk could contribute to the defence against reactivation of HSV in the orolabial epithelia. The Panel concludes that a cause and effect relationship has not been established between the consumption of the low-fat fermented milk, which is the subject of the health claim, and defence against reactivation of HSV in the orolabial epithelia.

Panel members at the time of adoption

Jean-Louis Bresson, Barbara Burlingame, Tara Dean, Susan Fairweather-Tait, Marina Heinonen, Karen Ildico Hirsch-Ernst, Inge Mangelsdorf, Harry McArdle, Androniki Naska, Monika Neuhäuser-Berthold, Grażyna Nowicka, Kristina Pentieva, Yolanda Sanz, Alfonso Siani, Anders Sjödin, Martin Stern, Daniel Tomé, Dominique Turck, Hendrik Van Loveren, Marco Vinceti and Peter Willatts
Panel on Dietetic Products, Nutrition and Allergies
Contact
nda [at] efsa.europa.eu
doi
10.2903/j.efsa.2016.4538
EFSA Journal 2016;14(7):4538
Question Number
On request from
Competent Authority of Italy following an application by Granarolo S.p.A
Competing interests
In line with EFSA's policy on declarations of interest, the Panel member Anders Sjödin did not participate in the development and adoption of this scientific opinion.