Evaluation of the revision of the BSE monitoring regime in Croatia


European Food Safety Authority
EFSA Journal
EFSA Journal 2016;14(2):4399
Panel Members
Ana Allende, Declan Bolton, Marianne Chemaly, Robert Davies, Pablo Salvador Fernández Escámez, Rosina Gironés, Lieve Herman, Kostas Koutsoumanis, Roland Lindqvist, Birgit Nørrung, Antonia Ricci, Lucy Robertson, Giuseppe Ru, Moez Sanaa, Marion Simmons, Panagiotis Skandamis, Emma Snary, Niko Speybroeck, Benno Ter Kuile, John Threlfall, and Helene Wahlström.
EFSA wishes to thank its BIOHAZ Panel (EFSA Panel on Biological Hazards) for endorsing this scientific report on 20 January 2016, and the members of the Working Group on the request for scientific and technical assistance concerning the revision of the BSE monitoring regime in Croatia: Angel Ortiz Peláez, Valentina Rizzi, Giuseppe Ru, Marion Simmons, Pietro Stella for the preparatory work on this scientific output, and the contributions of EFSA’s contractor: Amie Adkin and Robin Simons (Animal and Plant Health Agency – the United Kingdom) and of EFSA staff members: Yves Van der Stede and Ana Belén García for the support provided to this scientific output.
Scientific Report of EFSA
On request from
European Commission
Question Number
28 January 2016
Published in the EFSA Journal
8 February 2016
Last Updated
16 February 2016. This version replaces the previous one/s.
European Food Safety Authority (EFSA), Parma, Italy
On 22 January 2015, Croatia submitted to the European Commission (EC) a request to revise its bovine spongiform encephalopathy (BSE) monitoring programme. The EC requested the European Food Safety Authority (EFSA) to provide scientific and technical assistance on an assessment of the capacity of the proposed revised monitoring programme in Croatia to allow the detection of BSE, both classical and atypical strains, with a design prevalence of at least one case per 100,000 animals in the adult cattle population of the EU26 group (EU25 and Croatia). Under this revision Croatia would stop testing all healthy slaughtered cattle and would test all ‘at risk’ cattle of active surveillance above 36 months of age. The EC resolved that the EU26 should be considered as a unique epidemiological unit for this assessment. Data related to the EU26 were updated to run the Cattle Transmissible Spongiform Encephalopathies Monitoring Model (C-TSEMM), previously applied to similar assessments. This model allows the estimation of the design prevalence of the same surveillance regime applied by a group of countries. Using data up to 2014, the current EU25 surveillance regime would allow the detection of BSE in the EU25 with a design prevalence of at least 1 per 3,769,555 of the cattle adult population, lower (i.e. more sensitive) than the minimum requirement of 1 case per 100,000. The addition of Croatia to the EU25 epidemiological unit (EU26) assuming the current EU25 surveillance regime resulted in an ability in EU26 to detect BSE with a design prevalence of at least 1 per 3,789,838 of the adult cattle population. It is recommended: [1] to run the C-TSEMM model on an annual basis with updated data; [2] to monitor MS data in order to evaluate the surveillance coverage and [3] to identify any shortcomings affecting the overall sensitivity of the surveillance system. 
BSE, Croatia, EU25, EU26, monitoring, prevalence, surveillance