Modification of the existing maximum residue levels for proquinazid in currants and gooseberries

Tabs

Article
European Food Safety Authority
EFSA Journal
EFSA Journal 2015;13(11):4280 [18 pp.].
doi
10.2903/j.efsa.2015.4280
Type
Reasoned Opinion
On request from
European Commission
Question Number
EFSA-Q-2015-00503
Approved
23 October 2015
Published
3 November 2015
Affiliation
European Food Safety Authority (EFSA), Parma, Italy
Note
Download Article (539.92 KB)
Abstract

In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State (EMS) Germany received an application from Landwirtschaftliches Technologiezentrum Augustenberg to modify the existing maximum residue levels (MRLs) for the active substance proquinazid in currants (black, red and white) and in gooseberries (green, red and yellow). Germany drafted an evaluation report in accordance with Article 8 of Regulation (EC) No 396/2005, which was submitted to the European Commission and forwarded to EFSA. According to EFSA the data are sufficient to derive a MRL proposal of 1.5 mg/kg for the proposed northern Europe use of proquinazid on currants and gooseberries, based on the residue trials on black currants. Adequate analytical methods are available to control proquinazid residues in the berries under consideration. Based on the risk assessment results, EFSA concludes that the proposed use of proquinazid on currants and gooseberries will not result in a consumer exposure exceeding the toxicological reference values and therefore is unlikely to pose a consumer health risk.

Summary

In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State (EMS) Germany received an application from Landwirtschaftliches Technologiezentrum Augustenberg to modify the existing maximum residue levels (MRLs) for the active substance proquinazid in currants (black, red and white) and in gooseberries (green, red and white). Germany drafted an evaluation report in accordance with Article 8 of Regulation (EC) No 396/2005, which was submitted to the European Commission and forwarded to the European Food Safety Authority (EFSA) on 2 September 2015.

EFSA bases its assessment on the evaluation report submitted by the EMS Germany, the DAR prepared under Directive 91/414/EEC, the conclusions on the peer review of the pesticide risk assessment and the conclusions from previous EFSA opinions on the active substance proquinazid.

The toxicological profile of proquinazid was assessed in the framework of the peer review under Directive 91/414/EEC and the data were sufficient to derive an acceptable daily intake (ADI) of 0.01 mg/kg bw per day and an acute reference dose (ARfD) of 0.2 mg/kg bw.

The metabolism of proquinazid in primary crops was investigated in the fruit (grapes) and cereals/grass (wheat) crop groups. Slightly different metabolic pathways were observed between both crops, since residues in wheat were mostly composed of proquinazid and its metabolite IN-MW977, while the metabolite IN-MW977 was not identified in grapes. Based on these data the residue definition for risk assessment in both crop groups was proposed by the peer review as ‘proquinazid and metabolite IN-MW977, expressed as proquinazid’ and as ‘proquinazid’ alone for monitoring. For the uses on berries, EFSA concludes that the metabolism of proquinazid is sufficiently addressed and the residue definitions for enforcement and risk assessment agreed during the peer review are applicable.

EFSA concludes that the submitted supervised residue trials on black currants are sufficient to derive a MRL proposal of 1.5 mg/kg on currants (black, red and white), extrapolated to gooseberries (green, red and white). Adequate analytical enforcement methods are available to monitor the residues of proquinazid in commodities under consideration at the validated limit of quantification (LOQ) of 0.01 mg/kg.

Proquinazid is stable under standard hydrolysis conditions and therefore for processed commodities the same residue definition as for raw commodities is applicable. Processing studies on berries were not provided and are not requested.

As the proposed uses of proquinazid are on permanent crops and since berries are normally not fed to livestock, the investigation of residues in rotational crops and in livestock is not required.

The consumer risk assessment was performed with revision 2 of the EFSA Pesticide Residues Intake Model (PRIMo). To calculate the chronic exposure, EFSA used median residue values (STMR) derived from the residue trials conducted on black currants. The acute exposure assessment was performed only with regard to the berries under consideration. The highest calculated chronic intake accounted for 12 % of the ADI (WHO Cluster B). An acute consumer risk was not identified in relation to the MRL proposals for currants and gooseberries, the highest calculated acute intake being 3 % of the ARfD for currants (DE, Child).

EFSA concludes that the intended use of proquinazid on currants (black, red and white) and gooseberries (green, red and white) will not result in a consumer exposure exceeding the toxicological reference values and therefore is unlikely to pose a concern for public health.

Keywords
proquinazid, currants, gooseberries, MRL application, consumer risk assessment
Print on demand
Number of Pages
18