Scientific Opinion on the substantiation of a health claim related to selenium and protection of DNA, proteins and lipids from oxidative damage pursuant to Article 14 of Regulation (EC) No 1924/2006

Tabs

Article
Panel on Dietetic Products, Nutrition and Allergies
EFSA Journal
EFSA Journal 2014;12(11):3890 [8 pp.].
doi
10.2903/j.efsa.2014.3890
Panel members at the time of adoption
Carlo Agostoni, Roberto Berni Canani, Susan Fairweather-Tait, Marina Heinonen, Hannu Korhonen, Sébastien La Vieille, Rosangela Marchelli, Ambroise Martin, Androniki Naska, Monika Neuhäuser-Berthold, Grażyna Nowicka, Yolanda Sanz, Alfonso Siani, Anders Sjödin, Martin Stern, Sean (J.J.) Strain, Inge Tetens, Daniel Tomé, Dominique Turck and Hans Verhagen.
Acknowledgements

The Panel wishes to thank the members of the Working Group on Claims: Carlo Agostoni, Jean-Louis Bresson, Susan Fairweather-Tait, Marina Heinonen, Ambroise Martin, Hildegard Przyrembel, Yolanda Sanz, Alfonso Siani, Anders Sjödin, Sean (J.J.) Strain, Inge Tetens, Hendrik Van Loveren, Hans Verhagen and Peter Willatts for the preparatory work on this scientific opinion.

Contact
Type
Opinion of the Scientific Committee/Scientific Panel
On request from
Member State - France
Question Number
EFSA-Q-2008-159
Adopted
30 October 2014
Published
19 November 2014
Affiliation
European Food Safety Authority (EFSA), Parma, Italy
Note
Download Article (348.67 KB)
Abstract

Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to selenium and protection of DNA, proteins and lipids from oxidative damage. The Panel considers that selenium is sufficiently characterised. Protection of body cells and molecules such as DNA, proteins and lipids from oxidative damage is a beneficial physiological effect. The Panel has previously assessed a claim on selenium and protection of DNA, proteins and lipids from oxidative damage with a favourable outcome. The target population was the general population. The Panel considers that the role of selenium in the protection of DNA, proteins and lipids from oxidative damage applies to all ages, including infants and young children (from birth to three years of age). The Panel concludes that a cause and effect relationship has been established between the dietary intake of selenium and protection of DNA, proteins and lipids from oxidative damage. The following wording reflects the scientific evidence: “Selenium contributes to the protection of DNA, proteins and lipids from oxidative damage”. The target population is infants and children up to three years of age.

Summary

Following an application from Specialised Nutrition Europe (formerly IDACE), submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to selenium and protection of DNA, proteins and lipids from oxidative damage.

The scope of the application was proposed to fall under a health claim referring to children’s development and health.

The food constituent that is the subject of the health claim is selenium, which is an essential nutrient and is measurable in foods by established methods. Selenium occurs naturally in foods and is authorised for addition to foods and for use in food supplements. The Panel considers that selenium is sufficiently characterised.

The claimed effect proposed by the applicant is “acts as an antioxidant to protect cells and tissues from oxidative damage”. The target population proposed by the applicant is infants and young children from birth to three years of age. The Panel considers that the protection of body cells and molecules such as DNA, proteins and lipids from oxidative damage is a beneficial physiological effect.

The Panel has previously assessed a claim on selenium and protection of DNA, proteins and lipids from oxidative damage with a favourable outcome. The target population was the general population. The Panel considered that the role of selenium as an indirect component of the antioxidant network was well established.

The Panel considers that the role of selenium in the protection of DNA, proteins and lipids from oxidative damage applies to all ages, including infants and young children (from birth to three years of age). Dietary Reference Values for selenium have been set for infants and young children.

The Panel concludes that a cause and effect relationship has been established between the dietary intake of selenium and protection of DNA, proteins and lipids from oxidative damage.

The following wording reflects the scientific evidence: “Selenium contributes to the protection of DNA, proteins and lipids from oxidative damage”.

In order to bear the claim, follow-on formulae should comply with the criteria of composition of follow-on formulae as laid down in Directive 2006/141/EC; nutritionally complete foods for special medical purposes intended for use by infants and nutritionally complete foods for special medical purposes other than those intended for use by infants should comply with the criteria of composition of these foods as laid down in Directive 1999/21/EC; processed cereal-based foods for infants and young children should comply with the criteria of composition of these foods as laid down in Directive 2006/125/EC; and other foodstuffs intended for infants and young children should provide at least 15 % of the reference values for nutrition labelling for foods intended for infants and young children as laid down in Directive 2006/141/EC. Such amounts can easily be consumed as part of a balanced diet. The target population is infants and children up to three years of age.

Keywords
selenium, antioxidant, oxidative damage, children, health claims
Print on demand
Number of Pages
8