Scientific opinion on GM cotton GHB614 × LLCotton25

Tabs

Article
GMO, cotton (Gossypium hirsutum L. and Gossypium barbadense L.), GHB614 × LLCotton25, herbicide tolerant, stack, Regulation (EC) No 1829/2003
First published in the EFSA Journal
16 May 2014
Adopted
11 April 2014
Type
Scientific Opinion
Abstract

Cotton GHB614 × LLCotton25 was produced by conventional crossing. The EFSA GMO Panel previously assessed the two single cotton events GHB614 and LLCotton25 and did not identify safety concerns. Integrity of the inserts was retained in the two-event stack cotton. No differences requiring further food and feed safety assessment were identified in the compositional analysis of cotton GHB614 × LLCotton25 except for a higher level of gossypol. The EFSA GMO Panel further assessed this difference and considers that it is of no safety relevance for animals and humans. Expression analysis and safety assessment of the newly expressed proteins identified no concerns regarding their potential toxicity and allergenicity. No indications of safety issues regarding the overall allergenicity of cotton GHB614 × LLCotton25 were identified. There are no indications of an increased likelihood of establishment and spread of feral cotton plants. Considering the scope of the application, potential interactions of cotton GHB614 × LLCotton25 with the biotic and abiotic environment were not considered a relevant issue. Environmental risks associated with an unlikely but theoretically possible horizontal gene transfer from cotton GHB614 × LLCotton25 to bacteria have not been identified. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of cotton GHB614 × LLCotton25.

Panel members at the time of adoption
Salvatore Arpaia, Andrew Nicholas Edmund Birch, Andrew Chesson, Patrick du Jardin, Achim Gathmann, Jürgen Gropp, Lieve Herman, Hilde-Gunn Hoen-Sorteberg, Huw Jones, Jozsef Kiss, Gijs Kleter, Martinus Lovik, Antoine Messéan, Hanspeter Naegeli, Kaare Magne Nielsen, Jaroslava Ovesna, Joe Perry, Nils Rostoks, Christoph Tebbe
Panel on Genetically Modified Organisms
Contact
gmo [at] efsa.europa.eu
doi
10.2903/j.efsa.2014.3680
EFSA Journal 2014;12(5):3680 [26 pp.].
Question Number
On request from
Competent Authority of the Netherlands for an application (EFSA-GMO-NL-2010-77) submitted by Bayer CropScience
Print on demand
Number of Pages
26