Reasoned opinion on the setting of MRLs for saflufenacil in various crops, considering the risk related to the metabolite trifluoroacetic acid (TFA)

saflufenacil, trifluoroacetic acid (TFA), MRL application, Regulation (EC) No 396/2005, consumer risk assessment
First published in the EFSA Journal
17 February 2014
13 February 2014
Reasoned Opinion

In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to perform a follow-up evaluation of saflufenacil with regard to the MRLs adopted recently by Codex Alimentarius Commission and the possible consumer health concerns regarding the metabolite trifluoroacetic acid (TFA). On the basis of the information available to EFSA and the current scientific knowledge, EFSA concludes that for the intended use of saflufenacil on the crops for which MRLs were requested in the framework of the MRL application (EFSA-Q-2011-00208), including the CXLs established by Codex Alimentarius Commission in 2012, the exposure to saflufenacil and its metabolite trifluoroacetic acid via the diet will not result in a consumer exposure exceeding the toxicological reference values derived for the parent compound saflufenacil and its metabolite and therefore is unlikely to pose a public health concern.

European Food Safety Authority
pesticides.mrl [at]
EFSA Journal 2014;12(2):3585 [58 pp.].
Question Number
On request from
European Commission