Scientific Opinion on the efficacy of Biosprint® (Saccharomyces cerevisiae) as a feed additive for cattle for fattening


Panel on Additives and Products or Substances used in Animal Feed
EFSA Journal
EFSA Journal 2013;11(4):3174 [6 pp.].
Panel Members
Gabriele Aquilina, Alex Bach, Vasileios Bampidis, Maria De Lourdes Bastos, Gerhard Flachowsky, Mikolaj Antoni Gralak, Christer Hogstrand, Lubomir Leng, Secundino López-Puente, Giovanna Martelli, Baltasar Mayo, Derek Renshaw, Guido Rychen, Maria Saarela, Kristen Sejrsen, Patrick Van Beelen, Robert John Wallace and Johannes Westendorf.

The Panel wishes to thank the members of the Working Group on Micro-Organisms including Andrew Chesson, Pier Sandro Cocconcelli and Ingrid Halle, for the preparatory work on this scientific opinion

Opinion of the Scientific Committee/Scientific Panel
On request from
European Commission
Question Number
13 March 2013
Published in the EFSA Journal
8 April 2013
European Food Safety Authority (EFSA), Parma, Italy

In a previous opinion on Biosprint, the FEEDAP Panel could not conclude on the efficacy of this additive when used in feed for cattle for fattening because of insufficient evidence. The European Commission has requested the European Food Safety Authority to re-evaluate the efficacy of the additive Biosprint® when used as a zootechnical additive (functional group: gut flora stabilisers) in diets for cattle for fattening at a minimum dose of 4.0 × 109 and a maximum dose of 9.0 × 109 CFU/kg complete feedingstuffs. In the present application, the results of two new efficacy studies performed in cattle for fattening were presented. Both showed significant improvements in final body weight, average daily gain and feed to gain ratio in Biosprint®-treated animals. Taking into account the positive result from the initial application, the FEEDAP Panel concludes that Biosprint® has the potential to be efficacious in cattle for fattening at the dose of 3.6 × 1010 CFU/head per day approximately equating to 4 × 109 CFU/kg feedingstuffs.

Zootechnical additive, gut flora stabiliser, Biosprint®, Saccharomyces cerevisiae, cattle for fattening, efficacy
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