Statement on the safety of the “conjugated linoleic acid (CLA) rich oils” Clarinol® and Tonalin® TG 80 as Novel Food ingredients

Conjugated Linoleic Acid, insulin sensitivity, blood lipids, novel food ingredient, Cognis, Lipid Nutrition
First published in the EFSA Journal
3 May 2012
Adopted
27 April 2012
Type
Statement

Abstract

Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to update its opinions on the safety of the conjugated linoleic acid (CLA)‑rich oils Clarinol® and Tonalin® TG 80 as Novel Food ingredients in the light of additional information provided by Member States to the European Commission. Clarinol® and Tonalin® TG 80 consist of approximately 80 % of the two CLA isomers c‑9,t‑11 and t-10,c-12 (1:1). The applicants suggested a daily intake of CLA of 3 g (3.75 g Clarinol®) and 3.5 g (4.5 g Tonalin® TG 80), respectively. The Panel considers that the additional information provided does not contain evidence thath would modify its previous conclusions regarding the effects of CLA on insulin sensitivity/glucose metabolism, blood lipids, lipid peroxidation, or subclinical inflammation. The Panel also considers that the new studies provided do not address longer-term (> 6 months) effects of CLA intake on insulin sensitivity, the arterial wall or liver steatosis, or the safety of CLA in type‑2 diabetic subjects, under the proposed conditions of use. The Panel concludes that the safety of Clarinol® and Tonalin® TG 80 has been established for the proposed uses and daily doses for up to six months. The safety of CLA consumption for periods longer than six months has not been established under the proposed conditions of use. The safety of CLA consumption by type‑2 diabetic subjects has not been established.

Panel members at the time of adoption

Carlo Agostoni, Jean-Louis Bresson, Susan Fairweather-Tait, Albert Flynn, Ines Golly, Hannu Korhonen, Pagona Lagiou, Martinus Løvik, Rosangela Marchelli, Ambroise Martin, Bevan Moseley, Monika Neuhäuser-Berthold, Hildegard Przyrembel, Seppo Salminen, Yolanda Sanz, Sean (J.J.) Strain, Stephan Strobel, Inge Tetens, Daniel Tomé, Hendrik van Loveren and Hans Verhagen.
Panel on Dietetic Products, Nutrition and Allergies
Contact
nda [at] efsa.europa.eu
doi
10.2903/j.efsa.2012.2700
EFSA Journal 2012;10(5):2700
Question Number
On request from
European Commission