The use of monomethylsilanetriol in food supplements in the light of new data provided

Tabs

Article
Monomethylsilanetriol, CAS No. 2445-53-6, silanetriol, methyl siliconate, methylsilanetriolate, methylsilanetriol, organic silicon, food supplements
First published in the EFSA Journal
5 July 2010
Adopted
23 June 2010
Type
Scientific Opinion
Abstract

The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion on the use ofmonomethylsilanetriol added for nutritional purposes to food supplements. The Panel was asked to evaluate towhich extent newly submitted information addresses the uncertainties expressed in its opinion on“Monomethylsilanetriol added for nutritional purposes to food supplements” in 2009. The Panel noted that thenewly submitted information relates to the bioavailability of silicon from, and to the toxicology of a sourcesubstance designated as monomethylsilanetriol orthohydroxybenzoate sodium salt (MSS). This substance differsfrom the substances evaluated by the Panel in 2009 since, unlike the substances evaluated previously, thecommercial form of MSS consists of an aqueous solution of salicylic acid (orthohydroxybenzoic acid),monomethylsilanetriol and sodium chloride. In the light of the newly submitted information and given the factthat the presence of salicylic acid in MSS may influence the bioavailability of silicon from MSS, and the toxicityof MSS, the Panel concluded that the new data are insufficient to fill the data gaps on the bioavailability ofsilicon from monomethylsilanetriol and on the toxicity of monomethylsilanetriol, which were highlighted in theopinion of 2009. The Panel therefore concludes, that the newly submitted information does not adequatelyaddress the uncertainties expressed in the previous opinion and would not justify the re-evaluation ofmonomethylsilanetriol added for nutritional purposes in food supplements.

Panel members at the time of adoption
F. Aguilar, B. Dusemund, P. Galtier, J. Gilbert, D.M. Gott, S. Grilli, R. Gürtler, J. König, C. Lambré, J-C. Larsen, J-C. Leblanc, A. Mortensen, D. Parent-Massin, I. Pratt, I.M.C.M. Rietjens, I. Stankovic, P. Tobback, T. Verguieva, R.A. Woutersen
Panel on Food Additives and Nutrient Sources Added to Food
Contact
ans [at] efsa.europa.eu
doi
10.2903/j.efsa.2010.1657
EFSA Journal 2010;8(7):1657 [13 pp.].
Question Number
On request from
European Commission
Print on demand
Number of Pages
13