Flavouring Group Evaluation 15, Revision 2 (FGE.15Rev2): Aryl-substituted saturated and unsaturated primary alcohol/aldehyde/acid/ester derivatives from chemical group 22
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 13 flavouring substances in the Flavouring Group Evaluation 15, including four additional substances considered in this Revision 2, using the Procedure in Commission Regulation (EC) No 1565/2000. None of the substances were considered to have genotoxic potential. The substances were evaluated through a stepwise approach (the Procedure) that integrates information on structure-activity relationships, intake from current uses, toxicological threshold of concern, and available data on metabolism and toxicity. The Panel concluded that the 13 substances [FL-no: 02.173, 05.154, 05.155, 05.156, 08.088, 08.089, 09.306, 09.339, 09.364, 09.690, 09.735, 09.836 and 09.837] do not give rise to safety concerns at their levels of dietary intake, estimated on the basis of the MSDI approach. Besides the safety assessment of these flavouring substances, the specifications for the materials of commerce have also been considered and for six substances [FL-no: 05.155, 08.088, 08.089, 09.306, 09.339 and 09.735], the composition of the stereoisomeric mixture has to be specified.